Caracas Simón Bolivar closed on June 24 after two powerful earthquakes struck Venezuela, causing extensive damage to the airport's infrastructure, according to the country's interim president, Delcy Rodríguez. The civil aviation authority issued a Notice to Air Missions (NOTAM) closing the airport's main runway 10R/28L, tentatively until July 2, although the secondary runway, 9/27, remains formally open.

Rodríguez did not provide a timeline for the airport's reopening. Videos circulating on social media showed significant structural damage to terminals at Caracas International Airport.

The airport is currently served by 22 carriers, including Laser Airlines, Fly to Los Roques, Avior Airlines, American Airlines, avianca airlines, Albatros Airlines, Copa Airlines, Conviasa, Aerocaribe (Venezuela), Aerolíneas Estelar, Iberia, LATAM Airlines, Wingo (Colombia), Venezolana, SASCA - Servicios Aeronauticos Sucre, Turkish Airlines, TAP Air Portugal, GOL Linhas Aéreas Inteligentes, Plus Ultra Líneas Aéreas, Air Europa, Caribbean Airlines, and Rutaca Airlines, according to ch-aviation schedules.

Copa Airlines announced on June 25 that it had suspended all flights to Caracas, Barquisimeto, Valencia Arturo Michelena International, and Barcelona José Antonio Anzoategui until further notice.

At least 164 people were killed and more than 900 injured after the twin earthquakes struck just 39 seconds apart. A magnitude 7.5 earthquake followed a magnitude 7.2 foreshock, triggering widespread destruction across the country.